Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287392 | 0.79 | HPGD (0.41) | HPGDTSHR | |
| SCHEMBL2513817 | 0.71 | — | — | |
| SCHEMBL27970887 | 0.71 | HPGD (0.38) | HPGDTSHR | |
| SCHEMBL15821070 | 0.69 | HPGD (0.43) | HPGDTSHRLMNA | |
| SCHEMBL1205789 | 0.69 | HPGD (0.46) | HPGDTSHRLMNA | |
| SCHEMBL179497 | 0.69 | HPGD (0.50) | HPGDTSHRLMNA | |
| SCHEMBL2827757 | 0.68 | HPGD (0.46) | HPGDTSHRLMNA | |
| SCHEMBL28861464 | 0.67 | — | — | |
| SCHEMBL16920575 | 0.67 | HPGD (0.44) | HPGDTSHRLMNA | |
| SCHEMBL21719751 | 0.67 | HPGD (0.44) | HPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1723199-A | 1,4-disubstituted piperidine derivatives and their use as 11-beta hsd1 inhibitors | ASTRAZENECA AB (SE) | 2006-01-18 | — | — | CN | disclosed |