Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL168103 | 1.00 | — | — | |
| Methane SCHEMBL27516770 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL10652206 | 0.97 | BLM (0.45) | BLMTSHRACHEBBOX1 | |
| Hydrochloric Acid SCHEMBL11030227 | 0.97 | — | — | |
| Ethylene SCHEMBL28749046 | 0.97 | BLM (0.45) | BLMTSHRACHEBBOX1 | |
| Hydrochloric Acid SCHEMBL27769287 | 0.97 | — | — | |
| Bromide SCHEMBL13280923 | 0.97 | BLM (0.45) | BLMTSHRACHEBBOX1 | |
| SCHEMBL72541 | 0.96 | — | — | |
| SCHEMBL16781185 | 0.96 | — | — | |
| SCHEMBL16781184 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107630349-A | Multifunctional cellulose fiber based on graphene oxide/nano zine oxide | 赵兵 | 2018-01-26 | — | — | CN | disclosed |
| CN-107460724-A | Multifunctional cellulose fiber based on nano zine oxide | 赵兵 | 2017-12-12 | — | — | CN | disclosed |
| CN-1711070-A | Shampoo composition | LION CORP (JP) | 2005-12-21 | — | — | CN | disclosed |