Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28792406 | 0.98 | TDP1 (0.59) | TDP1 | |
| Cyclooctane SCHEMBL21693719 | 0.83 | TDP1 (0.81) | TDP1 | |
| Tert-Butyl Formate SCHEMBL30378535 | 0.75 | TDP1 (1.00) | TDP1 | |
| Tert-Butyl Formate SCHEMBL1671 | 0.75 | — | — | |
| SCHEMBL7104179 | 0.74 | ALDH1A1 (0.44) | EPHX1KMT2A | |
| Tert-Butyl Formate SCHEMBL28465801 | 0.72 | — | — | |
| Tert-Butyl Formate SCHEMBL9398245 | 0.72 | — | — | |
| Tert-Butyl Formate SCHEMBL15687802 | 0.72 | — | — | |
| Tert-Butyl Formate SCHEMBL4984399 | 0.72 | — | — | |
| Tert-Butyl Formate SCHEMBL17956883 | 0.72 | TDP1 (0.68) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111155-B | A kind of synthetic method of 4,7- diaza spiro [2.5] octane -7- t-butyl formate | 武汉工程大学 | 2018-12-14 | — | — | CN | claimed |
| CN-105111155-A | Synthesis method of tert-butyl 4,7-diazaspiro[2.5]octyl-7-formate | WUHAN INST TECHNOLOGY | 2015-12-02 | — | — | CN | claimed |
| CN-116730927-A | Novel method for efficiently synthesizing 4, 7-diazaspiro [2.5] octane hydrochloride | 广州佳途科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-111943894-A | Synthesis method of 4, 7-diazaspiro [2.5] octane compound | 南京爱德程医药科技有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111943893-A | Synthesis method of 4, 7-diazaspiro [2.5] octane compound | 南京爱德程医药科技有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-108863958-B | Preparation method of 4, 7-diazaspiro [2.5] octane derivative | 南京药石科技股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-109641873-A | N- (pyridine -2- base) pyridine-sulfamide derivative and its purposes for disease treatment | 诺华股份有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105111155-B | A kind of synthetic method of 4,7- diaza spiro [2.5] octane -7- t-butyl formate | 武汉工程大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-105111155-B | A kind of synthetic method of 4,7- diaza spiro [2.5] octane -7- t-butyl formate | 武汉工程大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108863958-A | A kind of preparation method of 4,7- diaza spiro [2.5] Octane derivatives | 南京药石科技股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-105408327-A | Substituted benzoxazoles | Bayer Pharma AG | 2016-03-16 | — | — | CN | disclosed |
| CN-105111155-A | Synthesis method of tert-butyl 4,7-diazaspiro[2.5]octyl-7-formate | WUHAN INST TECHNOLOGY | 2015-12-02 | — | — | CN | disclosed |
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |
| CN-102439008-B | 1,2, 4-triazolo [4,3-a ] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders | ORTHO MCNEIL JANSSEN PHARM | 2015-04-29 | — | — | CN | disclosed |
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-102439008-A | 1,2, 3-triazolo [4,3-a ] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders | ORTHO MCNEIL JANSSEN PHARM | 2012-05-02 | — | — | CN | disclosed |
| CN-101880277-A | Aza spiro alkane derivatives as inhibitors of metalloproteinase | INCYTE CORP | 2010-11-10 | — | — | CN | disclosed |
| CN-1870896-A | Hydroxypyridopyrrolopyrazinedione compounds useful as HIV integrase inhibitors | MERCK & CO INC (US) | 2006-11-29 | — | — | CN | disclosed |
| CN-1863532-A | Azaspiroalkane derivatives as metalloproteinase inhibitors | INCYTE COPORATION (US) | 2006-11-15 | — | — | CN | disclosed |