Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | FLT4 | P35916 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25461252 | 0.85 | KDM4E (0.48) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25461166 | 0.84 | KDM4E (0.47) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL19094354 | 0.83 | KDM4E (0.48) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29395390 | 0.83 | KDM4E (0.48) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25461430 | 0.82 | KDM4E (0.39) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25461209 | 0.81 | IGF1R (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25461393 | 0.81 | KDM4E (0.39) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25462246 | 0.80 | KDM4E (0.38) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL158912 | 0.79 | BCHE (0.58) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29986041 | 0.79 | BCHE (0.58) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863799-B | Chromancarboxylic acid derivatives for the treatment of diabetes and lipid disorders | SK CORP | 2010-09-22 | — | — | CN | disclosed |
| CN-1863799-A | Chromancarboxylic acid derivatives for the treatment of diabetes and lipid disorders | SK CORP (KR) | 2006-11-15 | — | — | CN | disclosed |