SCHEMBL29395390

SCHEMBL29395390

c1ccc2c(-c3cccc4c3oc3ccccc34)nccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
MAPT P10636 5/20 0.48
ALDH1A1 P00352 4/20 0.48
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
GAA P10253 1/20 0.48
ALOX5 P09917 2/20 0.46
NPC1 O15118 5/20 0.43
RAB9A P51151 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
GPR55 Q9Y2T6 1/20 0.43
GLA P06280 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PIK3CD O00329 1/20 0.41
PIK3CB P42338 1/20 0.41
PRKDC P78527 1/20 0.41
BCHE P06276 2/20 0.40
ADK P55263 1/20 0.40
CDK2 P24941 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19094354 1.00 KDM4E (0.48) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22156247 0.85 AHR (0.47) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22096474 0.85 CYP1A2 (0.44) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL14956922 0.85 KDM4E (0.51) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL25461188 0.84 NPC1 (0.46) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL17666809 0.84 KDM4E (0.43) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL30051501 0.84 KDM4E (0.43) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL27639722 0.83 KDM4E (0.46) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22170799 0.82 CYP2A6 (0.44) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22316452 0.82 KDM4E (0.41) KDM4EMAPTALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4200310-B1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS UNIV HONG KONG (CN) 2025-11-05 EP claimed
CN-116157490-A Spiro metallized iridium emitters for OLED applications 香港大学 2023-05-23 CN claimed
WO-2022037613-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (CN) 2022-02-24 WO claimed
CN-116157490-A Spiro metallized iridium emitters for OLED applications 香港大学 2023-05-23 CN disclosed
WO-2022037613-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (CN) 2022-02-24 WO disclosed