Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242695 | 0.89 | TLR7 (0.41) | CYP3A4GRM4KITPDGFRBPDGFRA | |
| SCHEMBL4240323 | 0.87 | TP53 (0.45) | CYP3A4GRM4MAPTDYRK1ATP53 | |
| SCHEMBL3867677 | 0.85 | BRD4 (0.43) | MAPTTP53GAANMT1MEN1 | |
| SCHEMBL1486497 | 0.84 | HRH3 (0.42) | CYP3A4GRM4DYRK1ANMT1ACSS2 | |
| SCHEMBL27640490 | 0.84 | NMT1 (0.40) | MAPTTP53GAANMT1SMN1; SMN2 | |
| SCHEMBL1486550 | 0.82 | NMT1 (0.38) | NMT1ACSS2MEN1KMT2ANMT2 | |
| SCHEMBL19968181 | 0.81 | TLR7 (0.44) | — | |
| SCHEMBL27725059 | 0.81 | TLR7 (0.42) | MAPTTP53GAASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL1486765 | 0.81 | TLR8 (0.43) | CYP3A4GRM4MAPTDYRK1ASMN1; SMN2 | |
| SCHEMBL1486523 | 0.80 | SMN1; SMN2 (0.47) | MAPTTP53SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1842336-A | Aryloxy and arylalkyleneoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-10-04 | — | — | CN | disclosed |