SCHEMBL1486497

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1486436	0.92	TLR7 (0.45)	HRH3CYP3A4TLR7GRM4DYRK1A
	SCHEMBL1486507	0.91	TLR7 (0.47)	HRH3CYP3A4TLR7GRM4DYRK1A
	SCHEMBL1486437	0.89	HRH3 (0.44)	HRH3CYP3A4GRM4DYRK1ANMT1
	SCHEMBL4240323	0.85	TP53 (0.45)	CYP3A4GRM4DYRK1A
	SCHEMBL27640403	0.84	CYP3A4 (0.39)	CYP3A4GRM4DYRK1ANMT1ACSS2
	SCHEMBL1486575	0.83	NMT1 (0.45)	HRH3TLR7NMT1ACSS2NMT2
	SCHEMBL1486578	0.83	TLR7 (0.60)	TLR7
	SCHEMBL1486585	0.83	NMT1 (0.42)	HRH3NMT1NMT2PDGFRBPDGFRA
	SCHEMBL1486468	0.82	HRH3 (0.39)	HRH3CYP3A4DYRK1ANMT1ACSS2
	SCHEMBL4251093	0.80	TLR7 (0.52)	TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.