Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647077 | 0.83 | LOXL2 (0.56) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| SCHEMBL21169876 | 0.83 | LOXL2 (0.56) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| SCHEMBL5635456 | 0.80 | LOXL2 (0.59) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL28785128 | 0.79 | HSD17B3 (0.37) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL2699985 | 0.78 | LOXL2 (0.62) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL26962331 | 0.78 | LOXL2 (0.58) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| SCHEMBL5649108 | 0.77 | LOXL2 (0.53) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| SCHEMBL3520542 | 0.77 | LOXL2 (0.53) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| SCHEMBL20259350 | 0.77 | LOXL2 (0.66) | LOXL2CYP4A11MEN1KMT2AMAPK1 | |
| SCHEMBL24258017 | 0.77 | LOXL2 (0.56) | LOXL2CYP4A11MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1751025-A | Diamine derivatives | DAIICHI SEIYAKU CO (JP) | 2006-03-22 | — | — | CN | disclosed |