Glycylsarcosine

Glycylsarcosine

SCHEMBL27640673

CCOC(=O)Cl.CN(CC(=O)O)C(=O)CN

nearest known ligand 0.37

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MVD P53602 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
AOC3 Q16853 3/20 0.33
ALOX15 P16050 1/20 0.33
CYP1A2 P05177 1/20 0.32
ALDH1A1 P00352 3/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CYP2D6 P10635 1/20 0.30
GLRA1 P23415 1/20 0.30
SLC6A9 P48067 1/20 0.30
OR51E2 Q9H255 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycylsarcosine SCHEMBL510835 0.83 MVD (0.43) MVDAOC3ALOX15LMNAGLRA1
Glycine SCHEMBL27706410 0.81 GLRA1 (0.48) ALOX15CYP1A2ALDH1A1LMNAHSD17B10
Glycylsarcosine SCHEMBL4161366 0.81 MVD (0.42) MVDAOC3ALOX15LMNAGLRA1
SCHEMBL27732065 0.80 CA12 (0.37) MVDCA12CA1CA2CA9
SCHEMBL25693305 0.76 CA12 (0.60) CA12CA1CA2CA9AOC3
Trimethylammonium SCHEMBL28310630 0.74 ALDH1A1 (0.48) CA12CA1CA2CA9ALOX15
Propionic Acid SCHEMBL28864540 0.72 FFAR3 (0.53) ALOX15CYP1A2ALDH1A1LMNAHSD17B10
Bicarbonate SCHEMBL11634536 0.72 ALDH1A1 (0.50) ALOX15CYP1A2ALDH1A1LMNAHSD17B10
SCHEMBL6601997 0.72 ALDH1A1 (0.50) ALOX15CYP1A2ALDH1A1LMNAHSD17B10
Hydrazine SCHEMBL28240037 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102274130-B Application of n- benzene sulfonyl-l-glutamic acid or saline thereof SHISEIDO CO LTD 2013-06-12 CN disclosed
CN-102274130-A Application of n- benzene sulfonyl-l-glutamic acid or saline thereof 2011-12-14 CN disclosed
CN-102266269-A Parakeratosis inhibitor and external composition for skin 2011-12-07 CN disclosed
CN-1886114-B Parakeratosis inhibitor and composition for external use on skin SHISEIDO CO LTD 2011-08-10 CN disclosed
CN-1886114-A Parakeratosis inhibitor and composition for external use on skin SHISEIDO CO LTD (JP) 2006-12-27 CN disclosed