Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291295 | 0.89 | LMNA (0.54) | KDM4ELMNAHSD17B10ACHEGRIN2B | |
| SCHEMBL30574898 | 0.80 | KDM4E (0.71) | KDM4ELMNAHSD17B10ACHESELL | |
| SCHEMBL226720 | 0.80 | KDM4E (0.71) | KDM4ELMNAHSD17B10ACHESELL | |
| SCHEMBL27661360 | 0.80 | KDM4E (0.62) | KDM4ELMNAHSD17B10SRD5A2ACHE | |
| SCHEMBL27661246 | 0.80 | KDM4E (0.62) | KDM4ELMNAHSD17B10ACHESELL | |
| SCHEMBL10706698 | 0.79 | SRD5A2 (0.49) | KDM4ELMNAHSD17B10SRD5A2SELL | |
| Water SCHEMBL4310345 | 0.79 | KDM4E (0.69) | KDM4ELMNAHSD17B10ACHESELL | |
| SCHEMBL13381377 | 0.78 | SRD5A2 (0.74) | KDM4ESRD5A2CA12CA1CA2 | |
| SCHEMBL3468841 | 0.78 | KDM4E (0.68) | KDM4ELMNAHSD17B10SRD5A2ACHE | |
| SCHEMBL7167952 | 0.78 | SRD5A2 (0.62) | LMNASRD5A2MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1856461-A | Cycloalkylene compounds as estrogen receptor modulators | SMITHKLINE BEECHAM CORP (US) | 2006-11-01 | — | — | CN | disclosed |