Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.73 |
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Dichlorobenzene SCHEMBL29138720 | 0.86 | LMNA (0.80) | LMNACYP2A6IDO1TSHRCA12 | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.85 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.85 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5144812 | 0.80 | LMNA (0.89) | LMNACYP2A6IDO1TSHRCA12 | |
| 1,4-Dichlorobenzene SCHEMBL8166345 | 0.80 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5414363 | 0.80 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL6230506 | 0.80 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL6228832 | 0.80 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL6534336 | 0.80 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL11577097 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100594899-C | Sustained release system and method for ocular delivery of carbonic anhydrase inhibitors | CONTROL DELIVERY SYS INC (US) | 2010-03-24 | — | — | CN | claimed |
| CN-1959469-A | Method for forming contact lenses comprising therapeutic agents | JOHNSON & JOHNSON VISION CARE (US) | 2007-05-09 | — | — | CN | claimed |
| CN-1756537-A | Sustained release systems and methods for ocular delivery of carbonic anhydrase inhibitors | CONTROL DELIVERY SYS INC (US) | 2006-04-05 | — | — | CN | claimed |
| CN-105142710-A | Lacrimal system drug delivery device | UNIV COLORADO REGENTS | 2015-12-09 | — | — | CN | disclosed |
| CN-103937025-A | Therapeutic agent-containing contact lenses and preparation method thereof | SHENZHEN INST OF ADV TECH CAS | 2014-07-23 | — | — | CN | disclosed |
| CN-100594899-C | Sustained release system and method for ocular delivery of carbonic anhydrase inhibitors | CONTROL DELIVERY SYS INC (US) | 2010-03-24 | — | — | CN | disclosed |
| CN-1959469-A | Method for forming contact lenses comprising therapeutic agents | JOHNSON & JOHNSON VISION CARE (US) | 2007-05-09 | — | — | CN | disclosed |
| CN-1756537-A | Sustained release systems and methods for ocular delivery of carbonic anhydrase inhibitors | CONTROL DELIVERY SYS INC (US) | 2006-04-05 | — | — | CN | disclosed |