Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805921 | 0.85 | SGMS2 (0.57) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL27723974 | 0.81 | SGMS2 (0.59) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL4230070 | 0.80 | MAPT (0.49) | NPC1HTTKMT2AMAPT | |
| SCHEMBL27996704 | 0.79 | MRGPRX4 (0.50) | SGMS2MAPTL3MBTL1RXRARXRB | |
| SCHEMBL19511860 | 0.76 | PTGER1 (0.49) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL11583825 | 0.76 | SGMS2 (0.56) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL12322221 | 0.75 | SGMS2 (0.53) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL30468871 | 0.75 | SGMS2 (0.67) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL71081 | 0.75 | SGMS2 (0.67) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL112903 | 0.74 | SGMS2 (0.66) | SGMS2NPC1HTTGAAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735408-A | Receptor function controlling agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-15 | — | — | CN | disclosed |