Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 12/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474252 | 0.88 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1ADRB1HTR3EHTR3B | |
| SCHEMBL4481238 | 0.79 | SMARCA2 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL13627466 | 0.78 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1 | |
| SCHEMBL13627511 | 0.77 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL27641781 | 0.76 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1 | |
| SCHEMBL13627464 | 0.76 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1 | |
| SCHEMBL13627468 | 0.75 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL4468943 | 0.74 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1 | |
| SCHEMBL13627493 | 0.74 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1 | |
| SCHEMBL13627517 | 0.72 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738804-A | Pyrazole compounds | VERNALIS CAMBRIDGE LTD (GB) | 2006-02-22 | — | — | CN | disclosed |