Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755537 | 0.89 | HTR6 (0.53) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL27771239 | 0.85 | HTR6 (0.56) | HTR6HTR1A | |
| SCHEMBL28755482 | 0.84 | HTR6 (0.60) | HTR6HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL27642981 | 0.83 | HTR6 (0.58) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL27623634 | 0.80 | HTR6 (0.55) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL28777649 | 0.79 | HTR6 (0.36) | HTR6HTR1A | |
| SCHEMBL28777480 | 0.77 | HDAC3 (0.36) | HTR6HTR1A | |
| SCHEMBL27643121 | 0.77 | HTR6 (0.53) | HTR6HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL27643113 | 0.75 | HTR6 (0.49) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL4322646 | 0.75 | HTR6 (0.58) | HTR6HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101298433-A | 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy | BIOVITRUM AB (SE) | 2008-11-05 | — | — | CN | disclosed |
| CN-100378074-C | 2-, 3-, 4-or 5-substituted N1- (phenylsulfonyl) indoles and their therapeutic use | BIOVITRUM AB (SE) | 2008-04-02 | — | — | CN | disclosed |
| CN-1714077-A | 2-, 3-, 4-or 5-substituted N1- (phenylsulfonyl) indoles and their therapeutic use | BIOVITRUM AB (SE) | 2005-12-28 | — | — | CN | disclosed |