Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3521154 | 0.81 | CNR1 (0.51) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| SCHEMBL3522572 | 0.80 | CNR1 (0.48) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL3521159 | 0.79 | CNR1 (0.47) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| SCHEMBL3523525 | 0.70 | CNR1 (0.59) | CNR1LMNACTSLCYP3A4CYP1A2 | |
| SCHEMBL13500869 | 0.69 | CNR1 (0.45) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL3523411 | 0.68 | CNR1 (0.44) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL5166456 | 0.68 | LMNA (0.40) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| SCHEMBL3522511 | 0.68 | CNR1 (0.45) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| SCHEMBL13500866 | 0.65 | CYP1A2 (0.40) | CNR1SLC6A4SLC6A2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL3517240 | 0.64 | CYP1A2 (0.39) | CNR1SLC6A4SLC6A2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1747926-A | Substituted amide compounds | MERCK & CO INC (US) | 2006-03-15 | — | — | CN | disclosed |