Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 7/20 | 0.37 |
| ▸ | MME | P08473 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20322838 | 0.82 | KDM4E (0.51) | PPARGPPARAALDH1A1KDM4EAPAF1 | |
| SCHEMBL6443526 | 0.82 | KDM4E (0.51) | PPARGPPARAALDH1A1KDM4EAPAF1 | |
| SCHEMBL4994011 | 0.82 | PPARG (0.40) | PPARGPPARAALDH1A1KDM4ERIPK1 | |
| SCHEMBL4987788 | 0.82 | PPARG (0.40) | PPARGPPARAALDH1A1KDM4ERIPK1 | |
| SCHEMBL27505056 | 0.77 | PPARG (0.46) | PPARGPPARAALDH1A1KDM4EAPAF1 | |
| SCHEMBL14885334 | 0.76 | PPARG (0.49) | PPARGPPARAALDH1A1KDM4ERIPK1 | |
| SCHEMBL27644896 | 0.76 | TAAR1 (0.39) | PPARGPPARAALDH1A1RIPK1L3MBTL1 | |
| SCHEMBL27665604 | 0.76 | KMT2A (0.45) | PPARGPPARAACEMMEKMT2A | |
| SCHEMBL11737506 | 0.74 | PPARG (0.49) | PPARGPPARAALDH1A1KDM4ERIPK1 | |
| SCHEMBL27665679 | 0.74 | SLC1A1 (0.51) | PPARGPPARAALDH1A1RIPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |