Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 7/20 | 0.42 |
| ▸ | ACE | P12821 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557270 | 0.84 | REN (0.42) | MMEACETBXAS1 | |
| SCHEMBL18557293 | 0.84 | REN (0.42) | MMEACETBXAS1 | |
| SCHEMBL27665599 | 0.84 | PPARA (0.50) | CPA1MMEACEPPARAPPARD | |
| SCHEMBL27665679 | 0.82 | SLC1A1 (0.51) | KMT2APPARAPPARG | |
| SCHEMBL1515224 | 0.81 | PPARA (0.53) | KMT2ATRPA1CPA1PPARAPPARD | |
| SCHEMBL6005381 | 0.81 | PPARA (0.53) | KMT2ATRPA1CPA1PPARAPPARD | |
| SCHEMBL4990406 | 0.81 | MME (0.41) | KMT2ACPA1TDP1MMEACE | |
| SCHEMBL4989491 | 0.81 | MME (0.41) | KMT2ACPA1TDP1MMEACE | |
| SCHEMBL8587665 | 0.79 | ENPEP (0.47) | KMT2ATRPA1CPA1MMEACE | |
| SCHEMBL23352301 | 0.77 | TRPA1 (0.50) | TRPA1CPA1TDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |