Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645221 | 0.97 | GRM2 (0.38) | GRM2DRD2DRD4DRD3CHRM4 | |
| SCHEMBL27645173 | 0.96 | GRM2 (0.38) | GRM2DRD2DRD4DRD3CHRM4 | |
| SCHEMBL27666088 | 0.96 | GRM2 (0.38) | GRM2DRD2DRD4DRD3CHRM4 | |
| SCHEMBL27666084 | 0.94 | GRM2 (0.40) | GRM2DRD2DRD4DRD3CHRM4 | |
| SCHEMBL27665936 | 0.86 | HRH3 (0.46) | GRM2DRD2 | |
| SCHEMBL27666169 | 0.85 | HRH3 (0.47) | GRM2DRD2DRD3 | |
| SCHEMBL27645120 | 0.84 | HRH3 (0.47) | GRM2DRD2 | |
| SCHEMBL27645136 | 0.84 | HRH3 (0.47) | GRM2DRD2 | |
| SCHEMBL28761481 | 0.83 | HRH3 (0.43) | ACHE | |
| SCHEMBL2097825 | 0.82 | GRM2 (0.36) | GRM2DRD2DRD4DRD3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |