Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645120 | 1.00 | HRH3 (0.47) | HRH3HRH1KCNH2ADRA1AADRA1B | |
| SCHEMBL27666169 | 0.99 | HRH3 (0.47) | HRH3HRH1KCNH2ADRA1AADRA1B | |
| SCHEMBL27665936 | 0.96 | HRH3 (0.46) | HRH3HRH1KCNH2ADRA1AADRA1B | |
| SCHEMBL28761481 | 0.92 | HRH3 (0.43) | HRH3HRH1KCNH2ADRA1AADRA1B | |
| SCHEMBL27666088 | 0.86 | GRM2 (0.38) | GRM2DRD2 | |
| SCHEMBL27645173 | 0.86 | GRM2 (0.38) | GRM2DRD2 | |
| SCHEMBL27645221 | 0.85 | GRM2 (0.38) | GRM2DRD2 | |
| SCHEMBL27644580 | 0.84 | GRM2 (0.39) | GRM2DRD2 | |
| SCHEMBL5011646 | 0.83 | HRH1 (0.48) | HRH3HRH1KCNH2ADRA1AADRA1B | |
| SCHEMBL5013338 | 0.83 | HRH1 (0.48) | HRH3HRH1KCNH2ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |