Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 15/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586620 | 0.86 | CASP3 (0.55) | CASP3MAPT | |
| SCHEMBL4587198 | 0.85 | CASP3 (0.56) | CASP3 | |
| SCHEMBL27644439 | 0.84 | CASP3 (0.55) | CASP3 | |
| SCHEMBL4594722 | 0.84 | CASP3 (0.48) | CASP3 | |
| SCHEMBL4587850 | 0.84 | CASP3 (0.60) | CASP3 | |
| SCHEMBL4593396 | 0.83 | CASP3 (0.54) | CASP3SMN1; SMN2 | |
| SCHEMBL27624584 | 0.80 | CASP3 (0.55) | CASP3SIRT2MAPT | |
| SCHEMBL4422343 | 0.80 | CASP3 (0.72) | CASP3SMN1; SMN2 | |
| SCHEMBL4593372 | 0.79 | CASP3 (0.49) | CASP3MAPTSMN1; SMN2 | |
| SCHEMBL4593727 | 0.77 | CASP3 (0.49) | CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756547-A | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA INC | 2006-04-05 | — | — | CN | claimed |
| CN-1756547-A | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA INC | 2006-04-05 | — | — | CN | disclosed |