Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669708 | 0.87 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL31377006 | 0.84 | TNF (0.43) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL5139143 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL30527261 | 0.81 | TNF (0.44) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL17427669 | 0.81 | TNF (0.44) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL16321276 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL29656951 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL11553887 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL1369573 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL27822527 | 0.79 | CYP1A2 (0.47) | ALDH1A1HPGDHSD17B10CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100340558-C | N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method | UNIV DONGNAN (CN) | 2007-10-03 | — | — | CN | disclosed |
| CN-1785998-A | N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method | UNIV DONGNAN (CN) | 2006-06-14 | — | — | CN | disclosed |