Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645203 | 0.87 | RAB9A (0.64) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27645193 | 0.85 | RAB9A (0.55) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2094261 | 0.83 | RPS6KB1 (0.44) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2094258 | 0.83 | RPS6KB1 (0.44) | RAB9ANPC1SMN1; SMN2RPS6KB1MAPT | |
| SCHEMBL27644961 | 0.80 | SCD (0.55) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27644895 | 0.80 | NPC1 (0.52) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27644341 | 0.77 | RAB9A (0.55) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13181131 | 0.77 | RAB9A (0.63) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4703345 | 0.77 | RAB9A (0.56) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4849763 | 0.77 | RAB9A (0.56) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |