Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.38 |
| ▸ | CCR3 | P51677 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666274 | 0.80 | MAPT (0.41) | CCR3SLC6A2SLC6A4GAASMN1; SMN2 | |
| SCHEMBL2088110 | 0.79 | HRH1 (0.37) | HRH1CCR3KCNH2EPHX2ACLY | |
| SCHEMBL2088107 | 0.79 | HRH1 (0.37) | HRH1CCR3KCNH2EPHX2ACLY | |
| SCHEMBL27666228 | 0.78 | SCD (0.40) | SCN9AFPR2PROKR1SLC6A2SLC6A3 | |
| SCHEMBL558603 | 0.70 | SMN1; SMN2 (0.43) | GAASMN1; SMN2 | |
| SCHEMBL27666298 | 0.70 | SSTR2 (0.36) | HRH1CCR3KCNH2ACLYSLC6A2 | |
| SCHEMBL27644980 | 0.69 | CTSS (0.42) | HRH3CHRM4 | |
| SCHEMBL27666262 | 0.68 | KDM4E (0.33) | SLC6A2SLC6A4SLC6A3HRH3SMN1; SMN2 | |
| SCHEMBL2096714 | 0.67 | MAPT (0.42) | HRH1CCR3KCNH2ACLYHRH3 | |
| SCHEMBL2096718 | 0.67 | MAPT (0.42) | HRH1CCR3KCNH2ACLYHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |