Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27343418 | 0.94 | GPR84 (0.53) | GPR84FFAR1GRIK1GRIK2SLC1A2 | |
| SCHEMBL27362313 | 0.88 | GPR84 (0.44) | GPR84FFAR1GRIK1GRIK2SLC1A2 | |
| SCHEMBL27308404 | 0.87 | GPR84 (0.43) | GPR84FFAR1GRIK1GRIK2SLC1A2 | |
| SCHEMBL27357032 | 0.83 | TET2 (0.44) | GPR84FFAR1GRIK1GRIK2SLC1A2 | |
| SCHEMBL27363392 | 0.82 | GPR84 (0.40) | GPR84FFAR1MAPT | |
| SCHEMBL8772485 | 0.82 | GPR84 (0.81) | GPR84FFAR1GRIK1GRIK2MAPT | |
| SCHEMBL8772473 | 0.82 | GPR84 (0.81) | GPR84FFAR1GRIK1GRIK2MAPT | |
| SCHEMBL9579859 | 0.82 | GPR84 (0.81) | GPR84FFAR1GRIK1GRIK2MAPT | |
| SCHEMBL29853894 | 0.82 | GPR84 (0.81) | GPR84FFAR1GRIK1GRIK2MAPT | |
| SCHEMBL27497065 | 0.80 | PTGS1 (0.41) | GPR84FFAR1SLC1A2SLC1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101914124-B | Nucleoside phosphonate conjugates as anti HIV agents | GILEAD SCIENCES INC | 2012-07-18 | — | — | CN | disclosed |
| CN-1780643-B | Antiviral phosphonate analogs | GILEAD SCIENCES INC | 2012-04-25 | — | — | CN | disclosed |
| CN-101935333-A | Nucleoside phosphonate conjugates as anti-hiv agent | GILEAD SCIENCES INC | 2011-01-05 | — | — | CN | disclosed |
| CN-101914124-A | Nucleoside phosphonate conjugates as anti-hiv agent | GILEAD SCIENCES INC | 2010-12-15 | — | — | CN | disclosed |
| CN-101031306-B | Nucleoside phosphonate conjugates as anti-HIV agents | GILEAD SCIENCES INC | 2010-09-22 | — | — | CN | disclosed |
| CN-101591281-A | Phosphonate compounds having immunomodulatory activity | GILEAD SCIENCES INC (US) | 2009-12-02 | — | — | CN | disclosed |
| CN-101410120-A | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES INC (US) | 2009-04-15 | — | — | CN | disclosed |
| CN-101381379-A | Kinase inhibitor phosphonate conjugates | GILEAD SCIENCES INC (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101031306-A | Nucleoside phosphonate conjugates as anti-HIV agents | GILEAD SCIENCES INC (US) | 2007-09-05 | — | — | CN | disclosed |
| CN-101027062-A | Phosphonate analogs of HIV inhibitor compounds | GILEAD SCIENCES INC (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-101027312-A | Antiviral compounds | GILEAD SCIENCES INC (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1933844-A | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES INC (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1819832-A | Kinase inhibitory phosphonate analogs | GILEAD SCIENCES INC (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1780643-A | Antiviral phosphonate analogs | GILEAD SCIENCES INC (US) | 2006-05-31 | — | — | CN | disclosed |
| CN-1780631-A | anticancer phosphonate analogs | GILEAD SCIENCES INC (US) | 2006-05-31 | — | — | CN | disclosed |
| CN-1780630-A | Phosphonate compounds having immunomodulatory activity | GILEAD SCIENCES INC (US) | 2006-05-31 | — | — | CN | disclosed |