Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541489 | 0.88 | TDP1 (0.72) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL700473 | 0.88 | TDP1 (0.72) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL31148308 | 0.88 | TDP1 (0.72) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL8565115 | 0.87 | TSHR (0.79) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| Methyl Alcohol SCHEMBL27492265 | 0.84 | TDP1 (0.67) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL146895 | 0.79 | TSHR (1.00) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL1101208 | 0.79 | TSHR (1.00) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL29359563 | 0.79 | TSHR (1.00) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL41402 | 0.79 | TSHR (0.59) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL29763129 | 0.79 | TSHR (0.59) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1775747-A | Industrialized method for producing 2, 6-dichloro phenyl nitrile | YANGZHOU TIANCHEN FINE CHEMICA (CN) | 2006-05-24 | — | — | CN | disclosed |