SCHEMBL700473

SCHEMBL700473

Cc1c(Cl)cccc1[N+](=O)[O-]

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.72
TSHR P16473 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
HSD17B10 Q99714 1/20 0.52
HPGD P15428 2/20 0.50
GPR35 Q9HC97 1/20 0.48
LMNA P02545 2/20 0.48
DHODH Q02127 1/20 0.48
MAPT P10636 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
NPC1 O15118 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 5/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
POLB P06746 2/20 0.47
HSP90AA1 P07900 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31148308 1.00 TDP1 (0.72) TDP1TSHRSMN1; SMN2HSD17B10HPGD
Methyl Alcohol SCHEMBL27492265 0.96 TDP1 (0.67) TDP1TSHRSMN1; SMN2HSD17B10HPGD
SCHEMBL27645573 0.88 TSHR (0.64) TDP1TSHRSMN1; SMN2HSD17B10HPGD
SCHEMBL27645574 0.85 ALDH1A1 (0.70) TDP1TSHRSMN1; SMN2HSD17B10HPGD
SCHEMBL472112 0.84 TDP1 (1.00) TDP1TSHRSMN1; SMN2HSD17B10GPR35
SCHEMBL4864448 0.81 TDP1 (0.57) TDP1TSHRSMN1; SMN2HSD17B10LMNA
SCHEMBL9075358 0.79 TDP1 (0.55) TDP1TSHRSMN1; SMN2HSD17B10HPGD
SCHEMBL9011766 0.79 ALDH1A1 (0.43) TDP1TSHRSMN1; SMN2HSD17B10HPGD
SCHEMBL6889978 0.79 ALDH1A1 (0.51) TDP1TSHRSMN1; SMN2HSD17B10HPGD
SCHEMBL58157 0.78 TDP1 (0.65) TDP1TSHRSMN1; SMN2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036511-A Method for synthesizing 2-nitro-6-chlorotoluene 湖北可赛化工有限公司 2026-05-15 CN claimed
CN-119263988-A Method for preparing 1-chloro-2-methyl-3, 4-dinitrobenzene through microchannel-nitration 合肥立方制药股份有限公司 2025-01-07 CN claimed
CN-119098166-A Method for preparing nonporous metal catalyst by using photo-deposition method and application of catalyst 浙江友联化学工业有限公司 2024-12-10 CN claimed
CN-118851913-A Method for preparing ultra-high purity 6-chloro-2-nitrotoluene by coupling melt crystallization 天津科技大学 2024-10-29 CN claimed
CN-118515568-B Preparation method of 3-chloro-2-methylaniline 天津深蓝工程技术有限公司 2024-09-17 CN claimed
CN-118515568-A Preparation method of 3-chloro-2-methylaniline 天津深蓝工程技术有限公司 2024-08-20 CN claimed
CN-118022636-A Reaction device for continuous multi-stage catalytic hydrogenation of halogenated nitrobenzene and application method thereof 浙江友联化学工业有限公司 2024-05-14 CN claimed
CN-118002029-A Fixed bed for continuous catalytic hydrogenation and hydrogenation reaction method thereof 浙江友联化学工业有限公司 2024-05-10 CN claimed
CN-111118076-B Method for biocatalytically reducing nitro compound 重庆博腾制药科技股份有限公司 2024-03-08 CN claimed
CN-115784846-B Preparation method of 2,6-dihydroxytoluene 安徽英特美科技有限公司 2024-01-16 CN claimed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US claimed
WO-2003087233-A2 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-10-23 WO claimed
US-6541240-B1 Biodenitrogenation using Pseudomonas; use in selective removal of contaminants from petroleum PETROLEO BRASILEIRO S.A.-PETROBRAS (BR) 2003-04-01 US claimed
EP-1106700-A2 Microbial cleavage of organic c-n bonds Petroleo Brasileiro S.A. - PETROBAS (BR) 2001-06-13 EP claimed
EP-0569792-B1 Process for the preparation of N-acylated p-aminophenols BAYER AG (DE) 1996-02-21 EP claimed
US-5302742-A Process for the preparation of N-acylated p-amino-phenols BAYER AKTIENGESELLSCHAFT (DE) 1994-04-12 US claimed
EP-0569792-A2 Process for the preparation of N-acylated p-aminophenols BAYER AG (DE) 1993-11-18 EP claimed
EP-0282303-B1 1,5-DIPHENYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-01-15 EP claimed
EP-0282303-A1 1,5-Diphenyl-1H-1,2,4-triazole-3-carboxamide derivatives and herbicidal composition containing the same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-09-14 EP claimed
US-4020107-A ACIDIC PHOSPHORUS COMPOUND DEHALOGENATION INHIBITOR E. I. DU PONT DE NEMOURS AND CO. (US) 1977-04-26 US claimed