Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976405 | 0.93 | FGFR1 (0.52) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL3045527 | 0.78 | FGFR1 (0.50) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL3035802 | 0.78 | FGFR1 (0.50) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL14283222 | 0.73 | FGFR1 (0.52) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL27645569 | 0.72 | PSMB8 (0.37) | FGFR1ALDH1A1SMN1; SMN2KMT2AHCAR1 | |
| SCHEMBL27645619 | 0.72 | FGFR1 (0.33) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL27645618 | 0.72 | CYP2C9 (0.34) | FGFR1ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL6117596 | 0.72 | FGFR1 (0.57) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL29346035 | 0.70 | FGFR1 (0.61) | FGFR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL4040299 | 0.70 | NOTUM (0.37) | FGFR1ALDH1A1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1784387-A | Novel benzimidazole derivatives | ASTRAZENECA AB (SE) | 2006-06-07 | — | — | CN | disclosed |