Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699296 | 0.89 | ALDH1A1 (0.50) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL27645537 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL69748 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ETSHRHPGD | |
| SCHEMBL28080888 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL11310071 | 0.79 | MAPT (0.52) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL6672586 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL28147295 | 0.77 | ALDH1A1 (0.78) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL21363125 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL6335112 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL27680472 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTPKMHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1753668-A | 1, 5-diaryl pyrrole-3-carboxamide derivatives and their use as cannabinoid receptor modulators | ASTRAZENECA AB (SE) | 2006-03-29 | — | — | CN | claimed |
| CN-1753668-A | 1, 5-diaryl pyrrole-3-carboxamide derivatives and their use as cannabinoid receptor modulators | ASTRAZENECA AB (SE) | 2006-03-29 | — | — | CN | disclosed |