Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216057 | 0.84 | HTT (0.50) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10316385 | 0.84 | HTT (0.57) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1617954 | 0.79 | ERN1 (0.64) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29466480 | 0.79 | HTT (0.62) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6891909 | 0.78 | CA1 (0.48) | HTTALDH1A1HPGDRAD52CA1 | |
| SCHEMBL1616441 | 0.78 | HTT (0.57) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1618022 | 0.78 | HTT (0.60) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13356593 | 0.77 | HTT (0.56) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17301353 | 0.76 | TUBB4A (0.62) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1180921 | 0.76 | ABL1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110343070-A | A kind of Antitubulin and the preparation method and application thereof | 山东大学 | 2019-10-18 | — | — | CN | claimed |
| CN-110343070-A | A kind of Antitubulin and the preparation method and application thereof | 山东大学 | 2019-10-18 | — | — | CN | disclosed |
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-100491355-C | Cyclic diamine compound having five-membered cyclic group | KOWA CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1522250-A | Cyclic diamine compound having five-membered cyclic group | ������������ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |