Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666765 | 0.93 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5554742 | 0.88 | MAPK13 (0.57) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL28758457 | 0.88 | MAPK13 (0.47) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5392484 | 0.86 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27645689 | 0.84 | MAPK13 (0.46) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5560947 | 0.83 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5559793 | 0.83 | MAPK13 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5559458 | 0.83 | MAPK13 (0.47) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27666766 | 0.82 | MAPK13 (0.46) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5554593 | 0.80 | MAPK13 (0.44) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422179-C | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | claimed |
| CN-1852907-A | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2006-10-25 | — | — | CN | claimed |
| CN-100422179-C | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |
| CN-1852907-A | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2006-10-25 | — | — | CN | disclosed |