Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560029 | 0.92 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5392484 | 0.87 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5559691 | 0.86 | MAPK13 (0.48) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5398127 | 0.86 | MAPK13 (0.55) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5409022 | 0.86 | MAPK13 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27645772 | 0.83 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5403371 | 0.83 | MAPK13 (0.53) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5398164 | 0.83 | NPC1 (0.50) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5396650 | 0.82 | MAPK13 (0.50) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5395278 | 0.82 | MAPK13 (0.48) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | claimed |