Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524961 | 0.98 | HDAC3 (0.34) | TSHRRECQLALDH1A1MEN1FAAH | |
| SCHEMBL28090046 | 0.92 | TSHR (0.44) | TSHRRECQLALDH1A1MEN1CYP1A2 | |
| SCHEMBL28172522 | 0.91 | TSHR (0.36) | TSHRALDH1A1LMNA | |
| SCHEMBL27407392 | 0.91 | SOAT1 (0.46) | POLBMEN1FAAHTP53CYP1A2 | |
| SCHEMBL321683 | 0.89 | SOAT1 (0.49) | TSHRPOLBMEN1FAAHTP53 | |
| SCHEMBL27352394 | 0.89 | SOAT1 (0.49) | TSHRPOLBMEN1FAAHTP53 | |
| SCHEMBL28145727 | 0.89 | SOAT1 (0.49) | TSHRPOLBMEN1FAAHTP53 | |
| SCHEMBL27361734 | 0.89 | SOAT1 (0.49) | TSHRPOLBMEN1FAAHTP53 | |
| SCHEMBL27525570 | 0.89 | SOAT1 (0.49) | TSHRPOLBMEN1FAAHTP53 | |
| SCHEMBL27577004 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917245-A | Methods for making saccharide-protein glycoconjugates | NOVARTIS AG | 2014-07-09 | — | — | CN | claimed |
| CN-103349780-A | Conjugation of streptococcal capsular saccharides | NOVARTIS VACCINES & DIAGNOSTIC | 2013-10-16 | — | — | CN | claimed |
| CN-101304765-B | Conjugation of streptococcal capsular saccharides | NOVARTIS VACCINES & DIAGNOSTIC | 2013-03-27 | — | — | CN | claimed |
| CN-101304765-A | Conjugation of streptococcal capsular saccharides | NOVARTIS VACCINES & DIAGNOSTIC (IT) | 2008-11-12 | — | — | CN | claimed |
| CN-103917245-B | Method for preparing glycoprotein glycoconjugate | 葛兰素史密丝克莱恩生物有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-105126097-A | INTEGRATION OF MENINGOCOCCAL CONJUGATE VACCINATION | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |
| CN-104736180-A | Meningococcal serogroup X conjugates | NOVARTIS AG | 2015-06-24 | — | — | CN | disclosed |
| CN-103917245-A | Methods for making saccharide-protein glycoconjugates | NOVARTIS AG | 2014-07-09 | — | — | CN | disclosed |
| CN-1976716-B | Combined meningococcal conjugates with common carrier protein | CHIRON SRL | 2014-07-09 | — | — | CN | disclosed |
| CN-102302776-B | Injectable vaccines against multiple meningococcal serogroups | NOVARTIS VACCINES & DIAGNOSTIC | 2014-06-18 | — | — | CN | disclosed |
| CN-101926988-B | Injectable vaccines against multiple meningococcal serogroups | NOVARTIS VACCINES & IT DIAGNOSTIC | 2014-06-04 | — | — | CN | disclosed |
| CN-101524534-B | Capsular polysaccharide solubilisation and combination vaccines | CHIRON SPA | 2014-05-28 | — | — | CN | disclosed |
| CN-101163508-A | Meningococcal conjugate vaccine | CHIRON SRL (IT) | 2008-04-16 | — | — | CN | disclosed |
| CN-1976724-A | Integration of meningococcal conjugate vaccines | CHIRON SRL (IT) | 2007-06-06 | — | — | CN | disclosed |
| CN-1976716-A | Combined meningococcal conjugates with common carrier protein | CHIRON SRL (IT) | 2007-06-06 | — | — | CN | disclosed |
| CN-1968711-A | Combination vaccines containing low dose of HIB conjugates | CHIRON SRL (IT) | 2007-05-23 | — | — | CN | disclosed |
| CN-1889975-A | Liquid vaccines for multiple meningococcal serogroups | CHIRON SRL (IT) | 2007-01-03 | — | — | CN | disclosed |
| CN-1809380-A | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages | CHIRON SRL (IT) | 2006-07-26 | — | — | CN | disclosed |
| CN-1767853-A | Mucosal meningococcal vaccines | CHIRON SRL (IT) | 2006-05-03 | — | — | CN | disclosed |
| CN-1764472-A | Injectable vaccines against multiple meningococcal serogroups | CHIRON SRL (IT) | 2006-04-26 | — | — | CN | disclosed |