Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 14/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479498 | 1.00 | CA1 (0.49) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL27646611 | 1.00 | CA1 (0.49) | CA1CA2CA7CTSKCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL27848409 | 0.91 | CA1 (0.42) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL73696 | 0.84 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL73697 | 0.84 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL75827 | 0.84 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL19166265 | 0.82 | CA1 (0.49) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL17951340 | 0.82 | CA1 (0.49) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL7515863 | 0.82 | CA1 (0.49) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL27713972 | 0.81 | ACACB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101754970-B | Macrocyclic indole derivatives for the treatment of hepatitis c infections | ANGELETTI P IST RICHERCHE BIO | 2013-07-10 | — | — | CN | disclosed |
| CN-102791711-A | 1, 7-diazacarbazoles and their use in the treatment of cancer | HOFFMANN LA ROCHE | 2012-11-21 | — | — | CN | disclosed |
| CN-101175724-B | pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-12-07 | — | — | CN | disclosed |
| CN-101801982-A | Macrocyclic indole derivatives for the treatment of hepatitis C infections | ANGELETTI P IST RICHERCHE BIO | 2010-08-11 | — | — | CN | disclosed |
| CN-101754970-A | The Macrocyclic indole derivatives that is used for the treatment of hepatitis C | ANGELETTI P IST RICHERCHE BIO | 2010-06-23 | — | — | CN | disclosed |
| CN-100390149-C | Indazole derivatives | KYOWA HAKKO KOGYO KK (JP) | 2008-05-28 | — | — | CN | disclosed |
| CN-101175724-A | Pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1777590-A | Indazole derivatives | KYOWA HAKKO KOGYO KK (JP) | 2006-05-24 | — | — | CN | disclosed |