Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647294 | 1.00 | CPB1 (0.46) | CPB1PREPCTSKF2CASP3 | |
| SCHEMBL3746843 | 0.93 | CPB1 (0.54) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3738296 | 0.93 | CPB1 (0.54) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3738299 | 0.93 | CPB1 (0.54) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3738297 | 0.93 | CPB1 (0.54) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3746840 | 0.93 | CPB1 (0.54) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3252082 | 0.90 | PREP (0.48) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3751193 | 0.90 | PREP (0.48) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3252081 | 0.90 | PREP (0.48) | CPB1PREPCTSKCASP3TSHR | |
| SCHEMBL3751199 | 0.90 | PREP (0.48) | CPB1PREPCTSKCASP3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1871215-B | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL MYERS SQUIBB CO | 2011-06-08 | — | — | CN | disclosed |
| CN-1871215-A | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL MYERS SQUIBB CO (US) | 2006-11-29 | — | — | CN | disclosed |