Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038093 | 1.00 | FAAH (0.35) | FAAHTRPV1LPAR2LPAR3LPAR1 | |
| SCHEMBL3024778 | 1.00 | FAAH (0.35) | FAAHTRPV1LPAR2LPAR3LPAR1 | |
| SCHEMBL95937 | 0.91 | — | — | |
| SCHEMBL1017534 | 0.82 | LPAR2 (0.33) | LPAR2LPAR3LPAR1SOAT1 | |
| SCHEMBL97123 | 0.81 | — | — | |
| SCHEMBL9618002 | 0.81 | FAAH (0.59) | FAAHTRPV1LPAR2LPAR3LPAR1 | |
| SCHEMBL11072895 | 0.81 | LPAR3 (0.55) | FAAHTRPV1LPAR2LPAR3LPAR1 | |
| SCHEMBL6744603 | 0.81 | FAAH (0.59) | FAAHTRPV1LPAR2LPAR3LPAR1 | |
| SCHEMBL10603998 | 0.81 | LPAR3 (0.55) | FAAHTRPV1LPAR2LPAR3LPAR1 | |
| SCHEMBL13048889 | 0.81 | FAAH (0.59) | FAAHTRPV1LPAR2LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1764458-A | Bicyclic piperidine derivatives as the melanocortin-4 receptor agonist | MERCK & CO INC (US) | 2006-04-26 | — | — | CN | disclosed |