Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519864 | 0.88 | LMNA (0.58) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL14490204 | 0.85 | LMNA (0.54) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL27951116 | 0.81 | LMNA (0.53) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL10839698 | 0.81 | AKR1C3 (0.62) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9388298 | 0.80 | ELANE (0.55) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL539733 | 0.80 | LMNA (0.59) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL30239922 | 0.79 | LMNA (0.63) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL16952895 | 0.79 | LMNA (0.63) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL3141164 | 0.79 | LMNA (0.63) | LMNACYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL11758957 | 0.78 | TDP1 (0.56) | LMNACYP3A4MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100562511-C | 2-aryl-acetic acids, their derivative and contain their pharmaceutical composition | DOMPE SPA (IT) | 2009-11-25 | — | — | CN | claimed |
| CN-1768026-A | 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them | DOMPE SPA (IT) | 2006-05-03 | — | — | CN | claimed |
| CN-100562511-C | 2-aryl-acetic acids, their derivative and contain their pharmaceutical composition | DOMPE SPA (IT) | 2009-11-25 | — | — | CN | disclosed |
| CN-1768026-A | 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them | DOMPE SPA (IT) | 2006-05-03 | — | — | CN | disclosed |