Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.91 |
| ▸ | DPP4 | P27487 | 1/20 | 0.91 |
| ▸ | APP | P05067 | 12/20 | 0.72 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | GMNN | O75496 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Caffeate SCHEMBL28088236 | 0.95 | TTR (0.94) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL30602576 | 0.95 | TTR (1.00) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL30286241 | 0.95 | TTR (1.00) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL782032 | 0.95 | TTR (1.00) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL782033 | 0.95 | TTR (1.00) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL31059266 | 0.95 | TTR (1.00) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL22196845 | 0.95 | TTR (1.00) | TTRDPP4APPAKR1B10AKR1B1 | |
| SCHEMBL4262076 | 0.93 | TTR (0.94) | TTRDPP4APPAKR1B10AKR1B1 | |
| SCHEMBL4262080 | 0.93 | TTR (0.94) | TTRDPP4APPAKR1B10AKR1B1 | |
| Ethyl Caffeate SCHEMBL28516367 | 0.91 | TTR (0.91) | TTRDPP4APPAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108992434-A | Application of caffeic acid 3, 4-dihydroxy phenethyl ester in preparation of medicine for preventing colorectal cancer | 浙江大学 | 2018-12-14 | — | — | CN | claimed |
| CN-101502506-A | Medical use of 3-(3,4-dihydroxyphenyl)-acrylic acid 2-(3,4-dihydroxyphenyl)-ethyl ester | XIAOYUAN LIAN (CN) | 2009-08-12 | — | — | CN | claimed |
| CN-1879672-A | Medicine containing effective components of sarcandra glabra, preparation method and application thereof | LIAN XIAOYUAN (CN) | 2006-12-20 | — | — | CN | claimed |
| CN-108992434-A | Application of caffeic acid 3, 4-dihydroxy phenethyl ester in preparation of medicine for preventing colorectal cancer | 浙江大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108992434-A | Application of caffeic acid 3, 4-dihydroxy phenethyl ester in preparation of medicine for preventing colorectal cancer | 浙江大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108992434-A | Application of caffeic acid 3, 4-dihydroxy phenethyl ester in preparation of medicine for preventing colorectal cancer | 浙江大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-102949384-A | Application of coffee acid 3, 4-dihydroxy benzene ethyl ester to preparation of antitumor drug | UNIV ZHEJIANG | 2013-03-06 | — | — | CN | disclosed |
| CN-101502506-B | Medical use of 3-(3,4-dihydroxyphenyl)-acrylic acid 2-(3,4-dihydroxyphenyl)-ethyl ester | XIAOYUAN LIAN | 2011-08-17 | — | — | CN | disclosed |
| CN-101543488-B | A medicine containing caffeic acid 3,4-dihydroxyl phenethyl ester and its uses | XIAOYUAN LIAN | 2011-03-02 | — | — | CN | disclosed |
| CN-1879672-B | Total polyphenol of effective parts of plant glabrous sarcandra herb as well as preparation method and application thereof | XIAOYUAN LIAN | 2010-06-16 | — | — | CN | disclosed |
| CN-101574381-A | Extractive of effective part of chloranthus glaber and preparation method thereof | JIANGZHONG PHARMACEUTICAL CO L (CN) | 2009-11-11 | — | — | CN | disclosed |
| CN-101543488-A | A medicine containing caffeic acid 3,4-dihydroxyl phenethyl ester and its uses | XIAOYUAN LIAN | 2009-09-30 | — | — | CN | disclosed |
| CN-101502506-A | Medical use of 3-(3,4-dihydroxyphenyl)-acrylic acid 2-(3,4-dihydroxyphenyl)-ethyl ester | XIAOYUAN LIAN (CN) | 2009-08-12 | — | — | CN | disclosed |
| CN-1879672-A | Medicine containing effective components of sarcandra glabra, preparation method and application thereof | LIAN XIAOYUAN (CN) | 2006-12-20 | — | — | CN | disclosed |