Ethyl Caffeate

Ethyl Caffeate

SCHEMBL782033

CCOC(=O)C=Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 1.00
DPP4 P27487 1/20 1.00
APP P05067 11/20 0.78
MAOB P27338 1/20 0.74
CYP3A4 P08684 1/20 0.73
CA12 O43570 1/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
CA7 P43166 1/20 0.69
CA9 Q16790 1/20 0.69
CA14 Q9ULX7 1/20 0.69
AKR1B10 O60218 1/20 0.65
AKR1B1 P15121 1/20 0.65
PTPN1 P18031 1/20 0.65
IAPP P10997 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Caffeate SCHEMBL31059266 1.00 TTR (1.00) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL30602576 1.00 TTR (1.00) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL22196845 1.00 TTR (1.00) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL30286241 1.00 TTR (1.00) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL782032 1.00 TTR (1.00) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL28088236 0.97 TTR (0.94) TTRDPP4APPMAOBCYP3A4
SCHEMBL4262080 0.97 TTR (0.94) TTRDPP4APPMAOBCYP3A4
SCHEMBL4262076 0.97 TTR (0.94) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL28516367 0.95 TTR (0.91) TTRDPP4APPMAOBCYP3A4
Ethyl Caffeate SCHEMBL27648151 0.95 TTR (0.91) TTRDPP4APPMAOBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
CN-120022380-A Biotin-streptavidin mediated stem cell nano drug-loading system and preparation and application thereof 洛兮医疗科技(杭州)有限公司 2025-05-23 CN claimed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP claimed
CN-115209890-B Shikonin, arylnaphthalene lignans and pharmaceutical compositions containing them for inhibiting expression of pro-inflammatory genes 宝洁公司 2024-12-17 CN claimed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US claimed
CN-118931618-A Application of caffeic acid ethyl ester as antioxidant in preparation of synthetic ester insulating oil, antioxidant synthetic ester insulating oil and preparation method of antioxidant synthetic ester insulating oil 广东电网有限责任公司 2024-11-12 CN claimed
WO-2024209462-A1 ANTI-BIOFILM POLYMER COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-10-10 WO claimed
CN-118557563-A Application of caffeic acid ethyl ester in preparation of medicines for treating pulmonary fibrosis and renal fibrosis 华信青云科技有限公司 2024-08-30 CN claimed
CN-118440373-A Method for preparing polyvinyl alcohol/caffeic acid phenethyl ester composite membrane in bionic lignification process 中国林业科学研究院林产化学工业研究所 2024-08-06 CN claimed
EP-3705130-B1 METHOD FOR SEPARATING EIGHT COMPONENTS IN CHINESE TRADITIONAL MEDICINE COMPOSITION SHIJIAZHUANG YILING PHARMACEUTICAL CO LTD (CN) 2024-07-17 EP claimed
US-20060172402-A1 Production of vanillin in microbial cells RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2006-08-03 US claimed
EP-1666051-A2 Remedies Takara Bio, Inc. (JP) 2006-06-07 EP claimed
WO-2004036979-A2 PRODUCTION OF VANILLIN IN MICROBIAL CELLS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2004-05-06 WO claimed
US-20040002423-A1 Remedies TAKARA BIO INC. (JP) 2004-01-01 US claimed
US-20030203857-A1 Polyphenols, derivatives, and/or salts as therapeutic or prophylactic agents, useful for treating a disease requiring enhancement for growth factor such as nerve growth factor and hepatocyte growth factor TAKARA BIO INC. (JP) 2003-10-30 US claimed
US-20030175777-A1 Eleutherosides as adjuncts for vaccines and immune modulation BONAGURA VINCENT R (US) 2003-09-18 US claimed
WO-2003074000-A2 ELEUTHEROSIDES AS ADJUNCTS FOR VACCINES AND IMMUNE MODULATION OMEGA PHARMACEUTICAL, INC. (US) 2003-09-12 WO claimed
CN-1422159-A Therapeutic agents TAKARA SHUZO CO (JP) 2003-06-04 CN claimed
EP-1283037-A1 REMEDIES TAKARA BIO INC. (JP) 2003-02-12 EP claimed
EP-1277473-A1 REMEDIES TAKARA BIO INC. (JP) 2003-01-22 EP claimed