Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565731 | 0.77 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL5648632 | 0.76 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7150452 | 0.72 | POLB (0.39) | — | |
| SCHEMBL5648887 | 0.71 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7849593 | 0.70 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL28756592 | 0.69 | PTGS2 (0.39) | PTGS2PTGS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6022329 | 0.68 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL29663770 | 0.66 | P2RY6 (0.41) | ALDH1A1MAPT | |
| SCHEMBL5559818 | 0.64 | PTGS1 (0.51) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8877336 | 0.62 | MAOB (0.42) | DDR1NR4A2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1768050-A | Benzopyran compounds for the treatment of inflammation | PHARMACIA CORP (US) | 2006-05-03 | — | — | CN | disclosed |