Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.57 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947401 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1HTTPKMKDM4E | |
| SCHEMBL9208149 | 0.83 | ALDH1A1 (0.69) | MAPTALDH1A1HTTPKMKDM4E | |
| SCHEMBL8181126 | 0.82 | ALDH1A1 (0.57) | MAPTALDH1A1HTTPKMKDM4E | |
| SCHEMBL27669265 | 0.81 | NR4A1 (0.63) | SLC9A1MAPTALDH1A1HTTPKM | |
| SCHEMBL27649026 | 0.81 | ALDH1A1 (0.67) | MAPTALDH1A1HTTPKMKDM4E | |
| SCHEMBL624093 | 0.80 | ALDH1A1 (0.65) | SOS1SLC9A1MAPTALDH1A1HTT | |
| SCHEMBL7405206 | 0.80 | ALDH1A1 (0.65) | MAPTALDH1A1HTTPKMKDM4E | |
| SCHEMBL27669260 | 0.79 | CYP2E1 (0.50) | MAPTALDH1A1HTTPKMKDM4E | |
| SCHEMBL282163 | 0.78 | SOS1 (0.66) | SOS1SLC9A1MAPTALDH1A1HTT | |
| SCHEMBL5043758 | 0.78 | ALDH1A1 (0.68) | SOS1SLC9A1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100519544-C | Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them | KOREA INST OF CHEMISTRY KUL KU (KR) | 2009-07-29 | — | — | CN | disclosed |
| CN-1902188-A | Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2007-01-24 | — | — | CN | disclosed |