Fluoride

Fluoride

SCHEMBL27649166

Cl[SiH](Cl)c1ccccc1.F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.37
ALDH1A1 P00352 2/20 0.33
DAO P14920 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
BBOX1 O75936 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32
EHMT1 Q9H9B1 1/20 0.32
LMNA P02545 2/20 0.32
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30
TRPV6 Q9H1D0 1/20 0.30
CYP1A2 P05177 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203456 0.97
SCHEMBL27546754 0.93
SCHEMBL11293210 0.93 TSHR (0.37) TSHRALDH1A1DAONAPRTBBOX1
SCHEMBL9064098 0.81 TSHR (0.36) TSHRALDH1A1
Diphenylamine SCHEMBL8410026 0.81 HSD17B10 (0.60) TSHRALDH1A1LMNACYP1A2TDP1
SCHEMBL2685390 0.78
SCHEMBL297217 0.76 TSHR (0.39) TSHRALDH1A1DAONAPRTBBOX1
SCHEMBL11296187 0.75 ESR1 (0.34)
SCHEMBL22830125 0.73 TSHR (0.37) TSHRALDH1A1DAONAPRTBBOX1
Water SCHEMBL9174447 0.73 TSHR (0.37) TSHRALDH1A1DAONAPRTBBOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101437858-B Aluminoxane compositions, their preparation, and their use in catalysis ALBEMARLE CORP 2011-05-25 CN disclosed
CN-1902241-B Haloaluminoxane compositions, their preparation and their use in catalysis ALBEMARLE CORP 2011-03-30 CN disclosed
CN-101437858-A Aluminoxane compositions, their preparation, and their use in catalysis ALBEMARLE CORP (US) 2009-05-20 CN disclosed
CN-1902241-A Haloaluminoxane compositions, their preparation and their use in catalysis ALBEMARLE CORP (US) 2007-01-24 CN disclosed