Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716208 | 0.77 | MAPT (0.44) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL1716511 | 0.69 | PSEN1 (0.53) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL29531707 | 0.66 | NPC1 (0.69) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL824375 | 0.66 | NPC1 (0.69) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL6591400 | 0.66 | NPC1 (0.56) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL28958196 | 0.65 | KDM4E (0.60) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL15606216 | 0.63 | TOP2A (0.51) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL543954 | 0.63 | IDO1 (0.59) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1102401 | 0.63 | NPC1 (0.68) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL28265560 | 0.63 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910165-A | Acylaminothiazole derivatives and their use as beta-amyloid inhibitors | SANOFI AVENTIS (FR) | 2007-02-07 | — | — | CN | disclosed |