O-Xylene

O-Xylene

SCHEMBL27650445

COC=O.Cc1ccccc1C

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
ACHE P22303 2/20 0.56
ALDH1A1 P00352 3/20 0.50
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
ESR1 P03372 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27476994 0.89 TSHR (0.43) TSHRACHEALDH1A1TDP1HSD17B10
O-Xylene SCHEMBL28309220 0.89 TSHR (0.43) TSHRACHEALDH1A1NPSR1KMT2A
Formic Acid Methyl Ester SCHEMBL28112146 0.84 ACHE (0.65) TSHRACHEALDH1A1LMNANPC1
Formic Acid Methyl Ester SCHEMBL29959384 0.84 CA1 (0.50) TSHRALDH1A1CA1CA2CA7
O-Tolylamine SCHEMBL28184600 0.84 TDP1 (0.62) TSHRACHEALDH1A1TDP1CYP3A4
O-Xylene SCHEMBL27935935 0.83 TSHR (0.56) TSHRACHEALDH1A1CA1CA2
Toluene SCHEMBL4302343 0.81 ACHE (0.58) TSHRACHEALDH1A1TDP1CYP3A4
O-Xylene SCHEMBL27935934 0.81 TSHR (0.53) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11804366 0.79 TSHR (0.67) TSHRACHEALDH1A1CA1CA2
Iodobenzene SCHEMBL28181435 0.79 PDE4B (0.37) TSHRALDH1A1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1874693-B Food products containing a fruit component TAKASAGO PERFUMERY CO LTD 2010-05-05 CN disclosed
CN-1874693-A Food products containing a fruit component TAKASAGO PERFUMERY CO LTD (JP) 2006-12-06 CN disclosed