Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616788 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL7982816 | 0.83 | — | — | |
| Methoxymethane SCHEMBL28080015 | 0.81 | ESR2 (0.38) | ESR1ESR2SMN1; SMN2CYP3A4ALDH1A1 | |
| Methyl Alcohol SCHEMBL27740726 | 0.79 | — | — | |
| Methyl Alcohol SCHEMBL27848048 | 0.72 | ESR1 (0.44) | ESR1ESR2SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL3108167 | 0.72 | — | — | |
| Isothiocyanate SCHEMBL27985981 | 0.72 | ALDH1A1 (0.30) | ESR1ESR2CYP3A4ALDH1A1TP53 | |
| Benzidine SCHEMBL27578833 | 0.72 | ALDH1A1 (0.73) | SMN1; SMN2CYP3A4ALDH1A1TP53TDP1 | |
| Biphenyl SCHEMBL28771697 | 0.69 | ALDH1A1 (0.69) | SMN1; SMN2CYP3A4ALDH1A1TDP1HTT | |
| Biphenyl SCHEMBL28663024 | 0.69 | ALDH1A1 (0.69) | SMN1; SMN2CYP3A4ALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103755800-B | Modified human interferon polypeptides and its purposes | AMBRX INC. (US) | 2016-02-24 | — | — | CN | disclosed |
| CN-103755800-A | Modified human growth hormone polypeptides and their uses | AMBRX INC | 2014-04-30 | — | — | CN | disclosed |
| CN-101107357-B | Free reactant for nucleic acid-templated synthesis | HARVARD COLLEGE | 2013-01-02 | — | — | CN | disclosed |
| CN-101107357-A | Free reactant for nucleic acid-templated synthesis | HARVARD COLLEGE (US) | 2008-01-16 | — | — | CN | disclosed |
| CN-1942589-A | Modified human growth hormone polypeptides and uses thereof | AMBRX INC (US) | 2007-04-04 | — | — | CN | disclosed |