Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208741 | 0.76 | KDM4E (0.52) | HSD17B10MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27745508 | 0.76 | GABRA5 (0.36) | GABRA5GABRB2HSD17B10MEN1KMT2A | |
| SCHEMBL28787873 | 0.74 | GABRA5 (0.35) | GABRA5GABRB2HSD17B10MEN1KMT2A | |
| SCHEMBL13368577 | 0.74 | — | — | |
| SCHEMBL23229537 | 0.70 | — | — | |
| Formic Acid SCHEMBL31557645 | 0.69 | KDM4E (0.32) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL27826012 | 0.69 | GABRR1 (0.41) | GABRA5GABRB2HSD17B10MEN1KMT2A | |
| SCHEMBL27555407 | 0.68 | — | — | |
| SCHEMBL27895065 | 0.68 | GABRR1 (0.39) | GABRA5GABRB2HSD17B10MEN1KMT2A | |
| SCHEMBL1082931 | 0.67 | PTGDR2 (0.57) | MEN1KMT2AALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579447-A | Ethynyl derivatives | HOFFMANN LA ROCHE | 2016-05-11 | — | — | CN | disclosed |
| CN-102209714-B | Triazine, pyrimidine and pyridine analogs and their use as therapeutic agents and diagnostic probes | UNIV BASEL | 2015-03-25 | — | — | CN | disclosed |
| CN-101405275-B | Triazolone Derivatives | EISAI R&D MAN CO LTD | 2011-11-09 | — | — | CN | disclosed |
| CN-101405275-A | Triazolone Derivatives | EISAI R&D MAN CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| CN-101133054-A | 1, 3-thiazole-5-carboxamides useful as cancer chemotherapeutic agents | BAYER PHARMACEUTICALS CORP (US) | 2008-02-27 | — | — | CN | disclosed |
| CN-1902201-A | Bicyclic pyrimidin-4-(3H)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (VR1) | MERCK SHARP & DOHME (GB) | 2007-01-24 | — | — | CN | disclosed |