Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.64 |
| ▸ | GCK | P35557 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SCD | O00767 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099022 | 0.87 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL1426929 | 0.84 | GCK (0.64) | RAB9ANPC1SMN1; SMN2HPGDGCK | |
| SCHEMBL22704311 | 0.84 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL4290205 | 0.83 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2HPGDKCNK3 | |
| SCHEMBL4755922 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL1426855 | 0.81 | GCK (0.63) | RAB9ANPC1SMN1; SMN2HPGDKCNK3 | |
| SCHEMBL12616591 | 0.81 | GCK (0.56) | RAB9ANPC1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2664578 | 0.81 | GCK (0.61) | RAB9ANPC1SMN1; SMN2HPGDGCK | |
| SCHEMBL2664748 | 0.81 | GCK (0.64) | RAB9ANPC1SMN1; SMN2HPGDGCK | |
| SCHEMBL2664561 | 0.81 | GCK (0.61) | RAB9ANPC1SMN1; SMN2HPGDGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101712657-A | heteroarylcarbamoylbenzene derivative | BANYU PHARMA CO LTD | 2010-05-26 | — | — | CN | disclosed |
| CN-100591671-C | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMA CO LTD | 2010-02-24 | — | — | CN | disclosed |
| CN-1777589-A | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMA CO LTD (JP) | 2006-05-24 | — | — | CN | disclosed |