Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673860 | 0.91 | GPR119 (0.59) | GPR119MAPTSIGMAR1STAT3LMNA | |
| SCHEMBL13556223 | 0.86 | GPR119 (0.63) | GPR119MAPTLMNAMEN1KMT2A | |
| SCHEMBL27652112 | 0.85 | GPR119 (0.57) | GPR119MAPT | |
| SCHEMBL1673803 | 0.85 | GPR119 (0.77) | GPR119MAPTLMNAPAK1 | |
| SCHEMBL1673664 | 0.83 | GPR119 (0.60) | GPR119MAPTLMNA | |
| SCHEMBL1674020 | 0.83 | GPR119 (0.76) | GPR119MAPTLMNAMEN1POLB | |
| SCHEMBL1673743 | 0.79 | GPR119 (0.59) | GPR119MAPTLMNA | |
| SCHEMBL1673883 | 0.79 | GPR119 (0.49) | GPR119MAPT | |
| SCHEMBL1673831 | 0.78 | GPR119 (0.83) | GPR119MAPTPOLBKMT2A | |
| SCHEMBL6041087 | 0.78 | GPR119 (0.77) | GPR119MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1835943-A | 1,2, 3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of diseases related thereto, such as diabetes and hyperglycemia | ARENA PHARM INC (US) | 2006-09-20 | — | — | CN | disclosed |