Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285393 | 0.90 | TP53 (0.38) | POLBLMNATP53ALDH1A1 | |
| SCHEMBL2767007 | 0.89 | LMNA (0.40) | POLBLMNATP53MAPTALDH1A1 | |
| SCHEMBL2765619 | 0.87 | POLB (0.41) | POLBLMNATP53MAPTALDH1A1 | |
| SCHEMBL2765646 | 0.84 | LMNA (0.43) | POLBLMNATP53MAPT | |
| SCHEMBL2765966 | 0.84 | LMNA (0.43) | POLBLMNATP53MAPTALDH1A1 | |
| SCHEMBL2768085 | 0.84 | LMNA (0.40) | POLBLMNATP53MAPT | |
| SCHEMBL2766124 | 0.84 | LMNA (0.44) | POLBLMNATP53MAPT | |
| SCHEMBL2765569 | 0.83 | LMNA (0.46) | POLBLMNATP53MAPT | |
| SCHEMBL2767137 | 0.83 | LMNA (0.46) | POLBLMNATP53MAPT | |
| SCHEMBL13376549 | 0.83 | TP53 (0.38) | POLBLMNATP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858890-B1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-04-14 | — | — | EP | disclosed |
| EP-1858890-A1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006089909-A1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-08-31 | — | — | WO | disclosed |