Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 6/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653046 | 0.84 | MEN1 (0.42) | WEE1CHEK1MEN1KMT2APOLB | |
| SCHEMBL27673137 | 0.83 | WEE1 (0.44) | WEE1CHEK1RETMEN1KMT2A | |
| SCHEMBL27673158 | 0.82 | WEE1 (0.45) | WEE1CHEK1RETMEN1KMT2A | |
| SCHEMBL27653148 | 0.81 | WEE1 (0.38) | WEE1CHEK1RETESR1KDR | |
| SCHEMBL27653131 | 0.80 | RET (0.56) | WEE1CHEK1RETMEN1KMT2A | |
| SCHEMBL27673150 | 0.80 | WEE1 (0.47) | WEE1CHEK1RETMEN1KMT2A | |
| SCHEMBL3873857 | 0.80 | MEN1 (0.46) | WEE1MEN1KMT2APOLBMAPT | |
| SCHEMBL27653121 | 0.78 | POLB (0.48) | WEE1CHEK1MEN1KMT2APOLB | |
| SCHEMBL27653080 | 0.77 | WEE1 (0.45) | WEE1CHEK1RETMEN1KMT2A | |
| SCHEMBL31609273 | 0.76 | FABP4 (0.39) | MEN1KMT2AHDAC6FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |