Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653144 | 0.88 | KDM4E (0.47) | METAP2MAPTPOLBATMMEN1 | |
| SCHEMBL27653121 | 0.82 | POLB (0.48) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL27653081 | 0.80 | WEE1 (0.42) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL27673089 | 0.80 | MAPT (0.46) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL27673132 | 0.80 | MAPT (0.46) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL27673125 | 0.79 | RXRA (0.52) | METAP2MAPTPOLBATMMEN1 | |
| SCHEMBL27673101 | 0.79 | MAPT (0.40) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL3875130 | 0.79 | POLB (0.52) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL3875840 | 0.79 | POLB (0.56) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL149177 | 0.78 | MEN1 (0.63) | MAPTPOLBATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |